Leo J Bolles Clinic, IV Chelation Therapy, Homeopathic Remedies, Naturopathy, Acupuncture, Nutrition and Allergy, Nutritional, Biochemical, Vitamin, Mineral, deficiencies, imbalances, heavy metal detox, detoxification The Leo J. Bolles Clinic

15611 Bel-Red Rd., Bellevue WA, 98008 (425)881-2224

A PREVENTIVE MEDICINE CENTER

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    Nutritional, Biochemical, Vitamin and Mineral deficiencies or imbalances can be a major factor in the prevention, control and cure of disease.
    The philosophy of the physicians at the center is to balance the body chemistry, obtain maximum organ function and improve the body's own immune system.
    The Bolles Clinic is a management company that provides management services for Independent contractor physicians and other practitioners.
    Each practitioner acts of his or her own authority and provides part or all of the services listed.
    All medical services are offered only by a licensed medical professional.
     

    Summary# 44982

    Keywords:

    COGNITIVE FUNCTION, AGING - Folic Acid, Folate

    Topic:

    Long-Term Folic Acid Supplementation Improves Cognitive Function in Older Subjects

    Reference:

    "Effect of 3-year folic acid supplementation on cognitive function in older adults in the FACIT trial: a randomized, double blind, controlled trial," Durga J, van Boxtel MPJ, et al, The Lancet, 2007; 369: 208-216. (Address: Division of Human Nutrition, Wageningen University, 6700 EV Wageningen, Netherlands. E-Mail: jane.durga@rdls.nestle.com ).

    Summary:

    In a randomized, double-blind, placebo-controlled study involving 818 subjects aged 50-70 years with raised plasma total homocysteine and normal serum vitamin B12 at screening, long-term supplementation with folic acid was found to improve age-related cognitive function. The participants were randomized to receive 800 micrograms/day folic acid or placebo for a period of 3 years. The 3-year change in memory, information processing speed and sensorimotor speed were observed to be significantly better in the folic acid supplemented group, compared to the placebo group. Additionally, plasma total homocysteine concentrations decreased by 26% in the folic acid-supplemented group. Thus, the authors of this study conclude, "We have shown that 3-year folic acid supplementation improves performance on tests that measure information processing speed and memory, domains that are known to decline with age."

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