Leo J Bolles Clinic, IV Chelation Therapy, Homeopathic Remedies, Naturopathy, Acupuncture, Nutrition and Allergy, Nutritional, Biochemical, Vitamin, Mineral, deficiencies, imbalances, heavy metal detox, detoxification The Leo J. Bolles Clinic

15611 Bel-Red Rd., Bellevue WA, 98008 (425)881-2224

A PREVENTIVE MEDICINE CENTER

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    Nutritional, Biochemical, Vitamin and Mineral deficiencies or imbalances can be a major factor in the prevention, control and cure of disease.
    The philosophy of the physicians at the center is to balance the body chemistry, obtain maximum organ function and improve the body's own immune system.
    The Bolles Clinic is a management company that provides management services for Independent contractor physicians and other practitioners.
    Each practitioner acts of his or her own authority and provides part or all of the services listed.
    All medical services are offered only by a licensed medical professional.
     

    Summary# 44990

    Keywords:

    ALZHEIMER'S DISEASE, DEMENTIA - Folate, Vitamin B6, Vitamin B12

    Topic:

    Higher Total Folate Intake May Reduce the Risk of Alzheimer's Disease in Older Persons

    Reference:

    "Relation of higher folate intake to lower risk of Alzheimer disease in the elderly," Luchsinger JA, Tang MX, et al, Arch Neurol, 2007; 64(1): 86-92. (Address: Taub Institute for Research of Alzheimer's Disease and the Aging Brain, Joseph P. Mailman School of Public Health, Columbia University, New York, NY, USA. E-Mail: jal94@columbia.edu ).

    Summary:

    In a prospective study involving 965 subjects 65 years or older without dementia at baseline, results indicate that higher total folate intake (dietary intake and supplement intake) may lower the risk of Alzheimer's disease (AD). Total, dietary, and supplemental intake of folate and vitamins B6 and B12 were assessed using food-frequency questionnaires. During 6.1 years of follow-up, 192 cases of incident AD were identified. Using Cox proportional hazards regression models adjusted for age, sex, education, ethnic group, the epsilon4 allele of apolipoprotein E, diabetes mellitus, hypertension, current smoking, heart disease, stroke, and vitamin B6 and B12 levels, subjects in the highest quartile of total folate intake showed a 50% reduced risk of AD, compared to subjects in the lowest quartile of intake. No associations were observed between the risk of AD with vitamin B6 and B12 levels. Thus, the authors of this study conclude, "Higher folate intake may decrease the risk of AD independent of other risk factors and levels of vitamins B6 and B12. These results require confirmation with clinical trials."

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