Leo J Bolles Clinic, IV Chelation Therapy, Homeopathic Remedies, Naturopathy, Acupuncture, Nutrition and Allergy, Nutritional, Biochemical, Vitamin, Mineral, deficiencies, imbalances, heavy metal detox, detoxification The Leo J. Bolles Clinic

15611 Bel-Red Rd., Bellevue WA, 98008 (425)881-2224

A PREVENTIVE MEDICINE CENTER

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    Nutritional, Biochemical, Vitamin and Mineral deficiencies or imbalances can be a major factor in the prevention, control and cure of disease.
    The philosophy of the physicians at the center is to balance the body chemistry, obtain maximum organ function and improve the body's own immune system.
    The Bolles Clinic is a management company that provides management services for Independent contractor physicians and other practitioners.
    Each practitioner acts of his or her own authority and provides part or all of the services listed.
    All medical services are offered only by a licensed medical professional.
     

    Summary# 44875

    Keywords:

    DNA DAMAGE, TOXICITY, RADIATION -Curcumin, Turmeric, Curcuma Longa, Spice, Curry

    Topic:

    Curcumin Protects Against Gamma-Radiation Induced DNA Damage

    Reference:

    "Protective effect of curcumin on gamma-radiation induced DNA damage and lipid peroxidation in cultured human lymphocytes," Srinivasan M, Rajendra Prasad N, Menon VP, Mutat Res, 2006 Sep 12; [Epub ahead of print]. (Address: Department of Biochemistry, Faculty of Science, Annamalai University, Annamalainagar 608 002, Tamil Nadu, India).

    Summary:

    In a study in which cultured human lymphocytes were exposed to gamma radiation which induced toxicity, DNA damage and increased lipid peroxidation, pre-treatment with curcumin - the active agent found in the curry spice, turmeric - was found to protect cells against cellular damage. Three different doses of gamma radiation were used (1, 2, 4Gy). At all 3 doses, DNA damage and lipid peroxidation were induced, with the greatest damage occurring at 4Gy irradiation. Cells were pre-treated with 3 different concentrations of curcumin (1, 5, and 10 mug/ml). The highest dose of curcumin - 10 mug/ml - was found to protect the cells against all 3 levels of radiation-exposed damage. A dose of 5 mug/ml curcumin protected the cells against 1Gy and 2Gy irradiation, and a dose of 1 mug/ml curcumin protected the cells against 1 Gy irradiation. The authors of this study conclude, "…Pretreatment with curcumin gives protection to lymphocytes against gamma-radiation induced cellular damage ."

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